Fluorescence In Situ Hybridization
FISH or Fluorescence In Situ Hybridization is a molecular cytogenetic technique that uses fluorescent probes that binds to specific regions of a chromosome. Fluorescent probe is a DNA sequences complementary to the regions of interest on the chromosome. This technique is used extensively in clinical cytogenetics and genetic testing for detection of submicroscopic chromosome abnormalities, which may not be detected by karyotype analysis.
FISH is used in prenatal and postnatal samples for detection of aneuploidy, microdeletion/microduplication syndromes, subtelomeric rearrangements as well as to characterize the imbalances identified by microarray testing. FISH is also used for testing disease-specific deletion/duplication.
FISH panels are available in blood, bone marrow, fresh tissue, or paraffin block in oncology specimens. FISH can provide diagnostic and prognostic information in patients with cancer.
At Advanced Genomics Institute and Laboratory Medicine (AGILE), our scientists have extensive experience across a wide spectrum of FISH based genetic tests. We offer one of the largest varieties of FISH based genetic tests. Our tests are available through our exclusive DNA and Genetic Diagnostics brand – Labassure.
Labassure has presence through partners in several cities, including New Delhi – NCR, Agra, Ahmedabad, Bhopal, Chandigarh, Indore, Jaipur, Jodhpur, Lucknow, Mumbai, Gurgaon, Guwahati, Rajkot and Trichy amongst others.