Recurrent Miscarriage

Pregnancy loss is common with approximately 25% of all pregnancies resulting in a miscarriage. Approximately 10% for women in the age group of 20-35 and nearly 50% for women in the age group of 35-40 yrs of age have a bad obstetric history or miscarriage. The risk of miscarriages increases with advancing maternal age.

Following tests are offered to evaluate recurrent pregnancy loss:

Testing Options

1. Cytogenetic testing of products of conception:

More than 60% of early miscarriages result from chromosome abnormalities. Following testing options are available for products of conceptions:

2. Peripheral blood karyotype of parents:

To evaluate the cause of recurrent pregnancy loss, parents should undergo peripheral blood karyotype analysis in order to detect if either is a carrier of a balanced structural chromosome abnormalities. Balanced translocations are found in about 5% of couples with recurrent miscarriages. This testing allows prediction and options for testing for subsequent pregnancies.

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