Aneuploidy, the abnormal gain or loss of chromosomes, is a major cause of early fetal demise. The most common type of chromosome abnormality in spontaneous abortions and has been observed in chromosomes, with 13,18, 21, X, and Y.
At times it is difficult to culture the specimen obtained from a product of conception. This test helps to detect common chromosomal defects from products of conception using Flourescent in Situ Hybridization (FISH) technique