This test is useful in cases of hematological maligancies with a suspected BCR/ABL Translocation. In such cases, a larger segment of a proto-oncogene, called ABL, on chromosome 9 is translocated to the BCR gene which is present on chromosome 22. The two gene segments are fused and ultimately produce a protein that is larger than the normal ABL protein with unregulated tyrosine kinase activity. Consequently, it results in disorders such as chronic myeloid leukemia (CML), Acute Lymphoblastic Leukemia (ALL) and Acute Myelogenous Leukemia (AML).
Flourescent in Situ Hybridization
Oncology, Clinical hematology, Medicine
Bone Marrow/Peripheral Blood in green top (Na-Heparin tube) 3-4 ml
LABASSURE is the diagnostics arm of Advanced Genomics Institute and Laboratory Medicine
(AGILE). Labassure provides high quality diagnostic testing for various medical specialties such
as pediatrics, gynecology, fetal medicine, obstetrics, infertility, oncology, ophthalmology,
infectious disorders amongst others.
LABASSURE is the diagnostics arm of Advanced GenomicsInstitute and Laboratory Medicine(AGILE). Labassure provides high quality diagnostictesting for various medical specialties suchas pediatrics, gynecology, fetal medicine, obstetrics,infertility, oncology, ophthalmology,infectious disorders amongst others