Array Options

Microarray_

Array Options

AGILE’s comprehensive Chromosomal Microarray Analysis (CMA) services includes testing and clinical interpretation services, which enables clinicans to make better diagnosis and treatment decisions. Using the latest cytogenetics solutions from Affymetrix®, AGILE makes diganostic decisions simple, effective and insightful.

CMA – High Definition (HD)cma-array-options-1

Highest gene coverage and exceptional performance

  • 2.6 million markers for copy number variations
  • 750,000 high performing SNPs with genotype accuracy >99%
  • Using CytoScan® HD Array from Affymetrix, USA

Most comprehensvie coverage for cancer and constitutional genes

  • 100% coverage of ISCA constitutional genes
  • 100% coverage of Cancer genes
  • 100% coverage of X Chromosome OMIM genes
  • 96% coverage of RefSeq genes

 

CMA – Low Definition (LD)

Whole-genome coverage with emphasis on cytogenetics relevant regionscma-array-options-2

  • 750,000 markers for copy number which includes
  • 200,000 high performing SNPs with genotype accuracy >99%
  • Using CytoScan® 750K Array from Affymetrix, USA

Enriched coverage for cancer and constitutional genes

  • 100% coverage of ISCA constitutional genes
  • 100% coverage of Cancer genes
  • 93% coverage of X Chromosome OMIM genes
  • 80% coverage of RefSeq genes

 

CMA – Ultra Low Definition (ULD)

Whole-genome coverage with focussed coverage for prenatal and miscarriage applicationscma-array-options-3

  • Using CytoScan® Optima Suite from Affymetrix, USA
  • 300,000 features covering  18,000 copy number markers
  • 148,000 SNP evenly spaced markers
  • Enhanced coverage of 396 regions of prenatal interest
  • Support detection of CNVs, elucidation of allelic imbalance
  • Supports identification if AOH or LOH